Build bio-inspired nanomachines
with nanopores and more!
We are a new lab starting from October 2023 at KU Leuven.
In our lab, we learn from nature to build motors and machines that mimic the critical functions of nature's motor proteins at the nanoscale.
read more about our research, click here
Techniques We Love
A solid-state nanopore is typically a nanometer-sized hole formed in a synthetic membrane (usually SiNx or SiO2).
Single-molecule localization microscopy (SMLM) describes a family of powerful imaging techniques that dramatically improve spatial resolution over standard, diffraction-limited microscopy techniques and can image biological structures at the molecular scale.
DNA origami is the nanoscale folding of DNA to create arbitrary two- and three-dimensional shapes at the nanoscale. The specificity of the interactions between complementary base pairs make DNA a useful construction material, through design of its base sequences. DNA is a well-understood material that is suitable for creating scaffolds that hold other molecules in place or to create structures all on its own.
More about our techniques will be added here soon.
Is there a way to design and build flow-driven active nanomachines from the bottom up, with complete control and understanding, while enabling their autonomous directional (rotary) motion as their biological counterparts?
In our latest paper, together with our collabrators, we present the first-ever rationally designed nanometer-sized turbine made out of DNA! [Read More...]
Can we use nanopores and the nanoscale flow in the to build machines and motors? In thhis paper, we show how to use a minimalistic DNA rotor and a nanopore to converts transmembrane potentials into mechanical work. [Read More...]
News and updates
Official start of the lab
First two master students Quinten Coveliers and Tom Claes joined the lab